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twalls - Thanks for posting your question on the forum!
As long as the destination you are attempting to reach is on a different subnet (even if it is off of the same interface), the AOS firewall should allow you to NAT this traffic. Would you be able to post your configuration to this thread for us to review? Remember to remove any sensitive information.
I went ahead and flagged this post as "Assumed Answered." If any of the responses on this thread assisted you, please mark them as Correct or Helpful as the case may be with the applicable buttons. This will make them visible and help other members of the community find solutions more easily. If you still need assistance, we would be more than happy to continue working with you on this - just let us know in a reply.